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KMID : 1195620100030030153
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Clinical and Experimental Otorhinolaryngology
2010 Volume.3 No. 3 p.153 ~ p.160
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Treatment Outcomes and Quality of Life in Oropharyngeal Cancer after Surgery-based versus Radiation-based Treatment
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Kim Tae-Wook
Youm Hye-Youn
Byun Ha-Young
Son Young-Ik
Baek Chung-Hwan
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Abstract
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Objectives: Advances in reconstruction and conservative surgery and the importance of quality of life (QOL) encouraged this reevaluation of surgery-based treatments for oropharyngeal cancer. We tried to compare treatment outcome and QOL after surgery-based versus radiation-based treatment in oropharyngeal cancer.
Methods: The 133 eligible patients were divided into surgery-based and radiotherapy (RT)-based treatment groups. Medical records were reviewed, and EORTC QLQ-C30 and HN65 questionnaires were completed for survivors. Three-year overall survivals, disease-free survivals, locoregional control rates, and QOL scores were compared between the two groups.
Results: Demographic data and overall stages were not significantly different between the two groups, and all survival rates were non-significantly different, either. The scores for most QOL items were equivalent, however, for a few items, scores were significantly better in surgery-based group.
Conclusion: The surgery-based group achieved equivalent treatment outcomes and slightly better QOL scores than the RT-based group. The results of this study suggest that surgery could still be considered as a first-line therapy for oropharyngeal cancer.
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KEYWORD
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Treatment outcome, Quality of life, Oropharyngeal cancer, Surgery, Radiation
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